Aging is a complex process that is still needed to be understood. There are many theories till date that explain this process. Some say that your heart has pre-decided beats, while others say that exposure to damaging oxidants and free radicals are responsible for aging with times. Actually, the most studied and proven theories are based on the cellular level. In addition to the free radical theory, there are certain other theories that support the fact of aging. The mitochondrial theory of aging explains the declining certain cellular systems like energy production leads to aging. Moreover, above all is the sirtuin theory of aging. It explains the concept better than many theories and gathering attention from many experts. Now let us explain what it says! Sirtuin and NAD are two powerful forces in healthy aging.
Sirtuin helps regulate cellular health!
Let’s see how sirtuin works and what is it exactly!! It is a type of protein but not a dietary protein that could be easily found in beans or meat. Basically sirtuin is present in molecules that work within your cells to perform different tasks.
- Cellular health
- Metabolic regulation
- Cardiovascular health
- DNA expressions
- Healthy aging
The aforementioned are primary tasks performed by Sirtuin in your body. When sirtuin was discovered, it was immediately nicknamed “the longevity genes”. One thing that is extremely interesting about sirtuin is that they are present in different organisms with certain yet different numbers, for example, bacteria have one, yeast has five and mice & humans have seven.
One of the most prominent functions of sirtuin includes autophagy (waste cleanup inside the cell). If cells won’t get cleaned up then certainly they will get blocked. In fact, more blockages will impact their ability to work. So, sirtuin is essential for autophagy that keeps the body cells work properly. Further, the function of sirtuin will lead to extreme benefits including:
- Enhanced mental focus or better concentration
- Motivation and positive mood
- Improved mental and physical energy level
- Maintaining cholesterol levels already in the healthy range
- Healthy vascular system and joint health
- Supporting the body’s healthy inflammation response
These benefits sound great, isn’t it? But you would be surprised to know that sirtuin declines by 60% as you age. So, the question arises that “is there any way to increase sirtuin”? Here comes NAD.
Nicotinamide Adenine Dinucleotide(NAD) is a cofactor that is essential for life. NAD plays an essential role in anti-aging. It coexists in two forms in your body cells:
- NAD+
- NADH
It is the ratio of these two forms of NAD is important for controlling the number of cells signaling pathways. It helps turn nutrients into energy and regulate the biological activity of other proteins. The critical works of a sirtuin cannot be performed without NAD+. Sirtuin relies on NAD+ and NAD plays an important role in metabolism to turn nutrients into energy. So, there is a clear connection between sirtuin and metabolism. So, clearly just increasing the level of NAD+ isn’t just important. Especially when it is about maintaining health as we age.
To help promote overall health NAD and sirtuin works together. NAD+ activates sirtuin activity that is crucial for metabolism activity that further promotes health through biological functions. Sirtuin delivers a long list of health benefits responsible for aging with time and it doesn’t work without NAD+. Basically, these two powerful components of cellular health are partners and work incredibly well for your bodies.
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