Started from one country and spread all over the world, Corona Virus have tremendously affected people’s life negatively. Scientist across the world made efforts to find a perfect antidote/ medicine and finally Pfizer/ BioNtech and Moderna vaccines have been developed and approved for emergency use authorization (EUA). They both are approved to be used by U.S Food and Drug Administration (FDA). With many similarities these medicines are now available for vaccination. Both of these are mRNA vaccines with some similarities yet they are different in many ways.
Important differences between the vaccines:
Both vaccines are made to work with same mechanism and contains mRNA (messanger, ribonucleic Acid). It is not associated with MMMBop. Each living cell or microorganism has an assemblage of RNA or DNA. This DNA is a library of blueprints to the protein parts. This further are copied by cells or microorganisms and put together as ribosomes. The key function of both medicines may be similar but there are many other things to know about both of these vaccines.
Difference Between – Pfizer & Moderna
Pfizer is required to be stored under -112 to -76 Fahrenheit temperature, whereas, Moderna is stored between -13 to -5 Fahrenheit which is much convenient than former. Pfizer is distributed in a five-dose vial where as Moderna need to be taken in 10 dozes. Here Pfizer is preferred over the other. It is required to dilute .9% sodium to Pfizer before it is administered whereas, moderna need not to be diluted.
According to FDA briefing document Pfizer can be used on people over 16 years of age and will be administered 21 days apart. At the same time Moderna is approved for use in people over the age of 18 and can be administered 28 days apart. There were 30,350 participants during the clinical trial of moderna and it was 94.5% effective where as Pfizer was 95% effective with 36,621 participants during its trial.
Side-effects of Moderna and Pfizer!
Injection site pain, fatigue, joint pain, fever, chills, headache and muscle pains are prominent side-effect of Pfizer vaccine. When we talk about Moderna then one can encounter almost similar side-effects other than fever. According to FDA the side-effects are generally reported after the second dose of vaccination. The severe after effects of Pfizer were reported between 0 to 4.6% participants and there were 2% to 9.6% participants of moderna who faced severe adverse effects.
According to FDA patients over the age of 65 may face the side-effects by Pfizer more than the younger age group and for moderna vaccine people above 55 years are more likely to encounter the adverse effects. When you undergo the vaccination make sure that you take dozes of same medicine each time. As the medicine is available now so, we hope to overcome the epidemic soon.
